Restoration Kit For Viome's Metabolic Fitness - DRI

BIOBOX Metabolic Fitness Restoration Kit

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Metabolic Fitness

Metabolic syndrome is a cluster of conditions where there is disequilibrium in the pathways in charge of managing energy consumption and storage. The modern metabolic syndrome causes insulin resistance, hypertension, abnormal
cholesterol, obesity, and elevated blood triglyceride levels. Increased abundance and ingestion of cheap processed food (mainly carbohydrates in the form of sugar) have led to increased metabolic disease around the world. Sedentary lifestyle, lack of proper sleep, increased stress, lack of adequate sunlight exposure, and frequent use of drugs like cigarettes and alcohol have also lead to more people suffering from metabolic syndrome. Recent research has also shown that an unhealthy microbiome plays a vital role in the development of metabolic syndrome.

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Why Is Our Metabolic System so Important?

The metabolic system is in charge of the regulation of the energy available to meet all of the requirements of the tissues, and also the row material sources used by cells to build new proteins, carbohydrates, and lipids. The food that we consume is metabolized by mechanical, chemical, and biological processes that make it possible to be absorbed and utilized by ourbody.

What Occurs if Metabolic Regulation is Hindered?

A complex interaction of genetics, epigenetics, diet, lifestyle, and environmental factors determines the development of multifactorial metabolic diseases such as diabetes, obesity, and metabolic syndrome.

  • Fasting Blood Glucose: >100mg/dl
  • Hemoglobin A1C: > 6.5%
  • Blood pressure: >140/ >90 mmHg
  • Blood pressure: >140/ >90 mmHg
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Which Is the Role of Human Gut Microbiome in Metabolic Fitness?

Proper metabolism (homeostasis) is ultimately dependent on various components regulating insulin sensitivity, inflammation levels, thermoregulation, redox potential, and energy regulation. Increasing evidence places our gut microbiome as an important modulator of the crosstalk between diet and the development of obesity and metabolic disorders. Many factors affect our microbiome, including diet, exercise frequency, antibiotic usage, fasting, genetics, sunlight exposure, stress, oral hygiene, and sleep hygiene.

Some specific metabolites have been associated with metabolic profiles and the presence of some bacterial species in the gut. One example is the link between the presence of high proportions of branched-chain amino acids (BCAAs) in serum and Prevotella copri or Bacteroides vulgatus abundance. It has been suggested that these species enhanced BCAA synthesis in the host and interestingly, both bacteria were also found to be enriched in insulin- resistant humans.

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